What TRIAD 10MG is used for?
It is used to treat:
- Depression in adults (major depressive episodes)
- Neuropathic pain in adults
- Chronic tension type headache prophylaxis in adults
- Migraine prophylaxis in adults
- Bed-wetting at night in children aged 6 years and above, only when organic causes, such as spina bifida and related disorders
Talk to your Doctor if you
- are allergic to TRIAD or any of the other ingredients of this medicine
- have had a heart attack (myocardial infarction)
- have heart problems such as disturbances in heart rhythm which are seen on an electrocardiogram (ECG), heart block, or coronary artery disease
- have slow heart rate, heart failure
- have a low level of potassium or magnesium, or a high level of potassium in your blood
- have an over active thyroid gland or receive thyroid medication.
- have thoughts of suicide and worsening of your depression, mania, bipolar disorder schizophrenia
- have thoughts about killing or harming yourself
- have narrow angle glaucoma (loss of vision due to abnormally high pressure in the eye)
- have epilepsy, a history of convulsions or fits
- have difficulty in passing urine
- have enlarged prostate
- severe liver, heart disease, diabetes
- have pylorus stenosis (narrowing of the gastric outlet) and paralytic ileus (blocked intestine)
- If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine
- If you have taken TRIAD during the last part of the pregnancy, the newborn may have withdrawal symptoms such as irritability, increased muscle tension, tremor, irregular breathing, poor drinking, loud crying, urinary retention, and constipation
- TRIAD is recommended in children and adolescents before 6 years of age only in the treatment of Bed-wetting at night
- If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines
Tell your doctor about any other medicine you are taking: Such as,
- monoamine oxidase inhibitors (MAOIs) e.g. phenelzine, iproniazid, isocarboxazid, nialamide or tranylcypromine (used to treat depression) or selegiline (used to treat Parkinson's disease)
- adrenaline, ephedrine, isoprenaline, noradrenaline, phenylephrine and phenylpropanolamine (these may be present in cough or cold medicine, and in some anaesthetics)
- medicine to treat high blood pressure for example calcium-channel blockers (e.g. diltiazem and verapamil), guanethidine, betanidine, clonidine reserpine and methyldopa
- anticholinergic drugs such as certain medicines to treat Parkinson’s disease and gastrointestinal disorders (e.g. atropine, hyoscyamine)
- thioridazine (used to treat schizophrenia)
- tramadol (painkiller)
- medicines to treat fungal infections (e.g. fluconazole, terbinafine, ketoconazole, and itraconazole)
- sedatives (e.g. barbiturates)
- antidepressants (e.g. SSRIs (fluoxetine, paroxetine, fluvoxamine), and bupropion)
- medicines for certain heart conditions (e.g. beta blockers and antiarrhythmics)
- cimetidine (used to treat stomach ulcers)
- methylphenidate (used to treat ADHD)
- ritonavir (used to treat HIV)
- oral contraceptives
- rifampicin (to treat infections)
- phenytoin and carbamazepine (used to treat epilepsy)
- John´s Wort (hypericum perforatum) – a herbal remedy used for depression
- thyroid medication
- medicines to treat irregular heartbeats (e.g. quinidine and sotalol)
- astemizole and terfenadine (used to treat allergies and hay fever)
- medicines used to treat some mental illnesses (e.g. pimozide and sertindole)
- cisapride (used to treat certain types of indigestion)
- halofantrine (used to treat malaria)
- methadone (used to treat pain and for detoxification)
- diuretics (“water tablets” e.g. furosemide)
- Always take this medicine exactly as your doctor has told you
- TRIAD can be taken with or without food
- Swallow the tablets with a drink of water. Do not chew or crush them
For Depression
Adults
- The recommended initial dose is 10 ,or 25 mg two times daily
- Depending on your response to the medicine, your doctor may gradually increase the dose to 150 mg per day divided in two doses
Elderly (above 65 years of age) and patients with cardiovascular disease
- The recommended initial dose is 10 mg – 25 mg daily
- Depending on your response to the medicine, your doctor may gradually increase the dose to a total daily dose of 100 mg divided in two doses
For Neuropathic pain, chronic tension type headache and migraine prophylaxis
Adults
- The recommended initial dose is 10 mg - 25 mg in the evening
- The recommended daily dose is 25 mg - 75 mg
- If you receive doses above 100 mg daily, your doctor may need to do more frequent follow-up with you
Elderly (above 65 years of age) and patients with cardiovascular disease
- The recommended initial dose is 10 mg – 25 mg in the evening
- If you receive doses above 75 mg daily, your doctor may need to do more frequent follow-up with you
Bed-wetting at night:
The recommended doses for children:
- aged 6 to 10 years: 10 mg – 20 mg daily. A suitable dosage form should be used for this age group
- aged 11 years and above: 25 mg – 50 mg
If you take more TRIAD
- If you take moreTRIAD or if someone else has taken your medicine, talk to your doctor immediately and you may need Medical attention
If you forget to take TRIAD
- If you forget to take a dose, take it as soon as you remember, unless it is time for your next dose
- Do not take a double dose to make up for a forgotten dose
If you stop taking TRIAD
- Do not stop taking TRIAD without talking to your doctor
Common side effects are,
- constipation.
- dizziness.
- dry mouth.
- feeling sleepy.
- difficulty peeing.
- headache.
- a disorder with excess antidiuretic hormone called syndrome of inappropriate antidiuretic hormone.
- large purple or brown skin blotches.
- decreased blood platelets.
- very low levels of granulocytes, a type of white blood cell.
- low levels of white blood cells.
- increased eosinophils in the blood.
- Protect from excess heat and light
- Keep out of reach of children
- Store at room temperature (15-25°C)
- Do not use this medicine after the expiry date
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