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R-cinex 450mg Capsule 10's
R-cinex 450mg Capsule 10's

R-cinex 450mg Capsule 10's

Infection Prescription (Rx) Required

Rifampicin+Isoniazid 450mg+300mg

NPR 137.10

Mfr: Lupin Ltd
10 capsule(s) in a strip
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What is R-CINEX 450mg?

  • R-CINEX 450mg contains Rifampicin and isoniazid which belongs to the group of medicine called Antibiotics which is used in the treatment of tuberculosis.

What R-CINEX 450mg is used for?

  • It is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. 

Before taking rifampin and Isoniazid, tell your doctor or pharmacist:

  • If you are allergic to it; or if you have any other allergies.
  • your medical history, especially of: diabetes, liver problems (e.g., hepatitis), HIV infection, history of alcohol use/abuse.
  • Rifampin may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.
  • During pregnancy, this medication should be used only when clearly needed. When this drug is taken during the last few weeks of pregnancy, the risk of bleeding in both mother and infant may be increased. Tell your doctor right away if you notice any bleeding in your newborn. Discuss the risks and benefits with your doctor.
  • It passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.
  • For children this drug can be use after dose adjustment.
  • It is not likely to cause any effect on drivers and machine users. consult your doctor for any inconvenience.
  • aprepitant, digoxin, praziquantel, ranolazine, sulfasalazine, tacrolimus, theophylline
  • certain anti-infectives (including chloramphenicol, clarithromycin, dapsone, doxycycline, linezolid, telithromycin, zidovudine
  • quinolones such as ciprofloxacin)
  • antiarrhythmics (such as disopyramide, mexiletine, quinidine)
  • antimalarial drugs (such as atovaquone, quinine)
  • anti-seizure drugs (such as phenytoin, phenobarbital, lamotrigine)
  • azole antifungals (such as itraconazole, ketoconazole, voriconazole)
  • benzodiazepines (such as midazolam), "blood thinners" (such as warfarin), calcium channel blockers (such as diltiazem, nimodipine, verapamil)
  • anti-cancer drugs (such as imatinib, irinotecan)
  • oral drugs for diabetes (such as repaglinide)
  • hormone replacement drugs (including estrogens such as conjugated estrogen
  • progestins such as medroxyprogesterone)
  • certain drugs for mental/mood disorders (including clozapine, haloperidol, tricyclic antidepressants such as amitriptyline)
  • opioid pain relievers (such as methadone), HIV NNRTIs (such as delavirdine, etravirine, nevirapine)
  • HIV protease inhibitors (such as atazanavir, ritonavir, saquinavir)
  • certain drugs for sleep (such as ramelteon, eszopiclone, zopiclone), among others.
  • Always take the medication as prescribed by the doctor or pharmacist.
  • Take the medication with water.
  • This medication is best taken on an empty stomach with a full glass of water 1 hour before or 2 hours after meals.
  • Diarrhea From An Infection With Clostridium Difficile Bacteria
  • Decreased Function Of The Adrenal Gland
  • Porphyria
  • Acquired Hemolytic Anemia, An Anemia Due To Destruction Of Red Cells
  • Anemia
  • A Type Of Blood Clotting Disorder Called Disseminated Intravascular Coagulation
  • Decreased Blood-Clotting From Low Vitamin K
  • Discoloration Of The Saliva
  • Discolored Sweat
  • Sputum Discoloration
  • An Abnormal Stool Color
  • Diarrhea
  • Stomach Cramps
  • A Skin Rash
  • Indigestion
  • Increased Risk Of Bleeding Due To Clotting Disorder
  • Large Purple Or Brown Skin Blotches
  • Decreased Blood Platelets
  • Very Low Levels Of Granulocytes, A Type Of White Blood Cell
  • Low Levels Of White Blood Cells
  • Low Levels Of A Type Of White Blood Cell Called Neutrophils
  • Mental Problems From Taking The Drug
  • A Disease With Shrinking And Weaker Muscles Called Myopathy
  • Inflammation Of The Blood Vessels
  • Increased Eosinophils In The Blood
  • Confusion
  • Behavioral Problems
  • A Change In Vision
  • Pink Eye
  • Tear Discoloration
  • A Sore Throat
  • A Sore Tongue
  • A Problem With Menstrual Periods
  • keep this medicine out of reach of children.
  • Donot use this medicine after expiry
  • Store in original package to protect from light
  • keep at room temperature (15-25°C)

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Disclaimer

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.