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Mitomycin 40mg Injection
Mitomycin 40mg Injection

Mitomycin 40mg Injection

Cancer/Oncology Prescription (Rx) Required

MITOMYCIN 10MG

NPR 3,593.10

Mfr: Cadila Healthcare Ltd (Zydus)
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What is MITOMYCIN 40mg?

  • MITOMYCIN 40mg contains Mitomycin which belongs to a group of medicines called anti-neoplastic agent

What MITOMYCIN is used for?

It is used as palliative cancer therapy (for the relief of symptoms) in:

  • advanced metastatic stomach cancer (stomach carcinoma)
  • advanced and/or metastatic breast cancer (breast carcinoma)
  • cancer of the respiratory tract (non-small cell bronchial carcinoma)
  • advanced cancer of the pancreas (pancreatic carcinoma)

It is also used for the prevention of a relapse in the case of superficial urinary bladder cancer after the ablation of tissue through the urethra (transurethral resection)

Talk to your Doctor, if you:

  • are allergic to any of the other ingredients of this medicine
  • are suffering from impaired lung, kidney or liver function
  • are undergoing radiation therapy
  • are being treated with other cytostatics (substances which inhibit cell growth/cell division)
  • have inflammation of the urinary bladder (in case of intravesical administration)
  • have been told that you have bone marrow depression
  • are immunized with live virus vaccine as this increase risk of infection
  • If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine
  • The use of MITOMYCIN in children and adolescents is not recommended
  • It may cause nausea and vomiting and thereby reduce your reaction times to such an extent that the ability to drive a motor vehicle or operate machinery is impaired. This applies in conjunction with alcohol

Tell your doctor if you are taking,

  • anti-cancer drugs (used to treat cancer)
  • vaccines
  • MITOMYCIN must only be given by a doctor or nurse
  • It is intended to be used for injection or infusion into a blood vessel (intravenous use) or for introduction into the urinary bladder (intravesical instillation).

 

  • shortness of breath
  • dry cough and crackles during breath-in (interstitial pneumonia)
  •  severe renal dysfunction (nephrotoxicity)
  • Blood disorders: inhibition of blood cell production in the bone marrow
  • decreased number of white blood cells (leucopenia) increasing the risk of infections
  • decreased number of platelets (thrombocytopenia) causing bruises and bleedings
  • nausea, vomiting
  • lung disorders presenting as shortness of breath, dry cough and inspiratory crackles (interstitial pneumonia)
  • dyspnea, cough, shortness of breath
  • skin rashes and irritation of the skin
  • numbness, swelling and painful redness on palms and soles (palmar-plantar erythema)
  • kidney disorders (renal dysfunction, nephrotoxicity, glomerulopathy, increased levels of creatinine in the blood)
  • inflammation of connective tissue (cellulitis) and death of tissue (tissue necrosis) following accidental injection into the surrounding tissue (extravasation).

 

  • inflammation of a mucous membrane (mucositis)
  • inflammation of the mucosa of the mouth (stomatitis)
  • diarrhoea, fever
  • hair loss (alopecia)
  • loss of appetite (anorexia)
  • life-threatening infection
  • blood poisoning (sepsis)
  • decrease in number of red blood cells sometimes together with acute renal dysfunction (hemolytic anemia, microangiopathic-hemolytic anemia), hemolytic uraemic syndrome
  • loss of cardiac function (heart failure) after previous therapy with other anti-cancer medicines (anthracyclines)
  • increase in blood pressure in the vasculature of the lungs, e.g., leading to shortness of breath, dizziness and fainting (pulmonary hypertension)
  • obstructive disease of the pulmonary veins (pulmonary veno-occlusive disease)
  • liver dysfunction
  • increased levels of liver enzymes (transaminases)

 

  • faintness
  • skin rash or hives, itching
  • swelling of lips
  • face and airway with difficulty in breathing
  • loss of consciousness

 

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  • Keep this medicine out of reach of children
  • Store at a room temperature of 15-25°C
Disclaimer

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.